As the 2000 Dietary Guidelines for Americans states, “Different foods contain different nutrients and other healthful substances. No single food can supply all the nutrients in the amounts you need” [66]. As indicated in Table 1, green leafy vegetables, dried beans and peas, and many other types of vegetables and fruits provide folate. In addition, fortified [...]
April 28, 2011
Beware of the interaction between vitamin B12 and folic acid Intake of supplemental folic acid should not exceed 1,000 micrograms (?g) per day to prevent folic acid from triggering symptoms of vitamin B12 deficiency [10]. Folic acid supplements can correct the anemia associated with vitamin B12 deficiency. Unfortunately, folic acid will not correct changes in the nervous [...]
April 28, 2011
Folic Acid and Cardiovascular Disease Cardiovascular disease involves any disorder of the heart and blood vessels that make up the cardiovascular system. Coronary heart disease occurs when blood vessels which supply the heart become clogged or blocked, increasing the risk of a heart attack. Vascular damage can also occur to blood vessels supplying the brain, and can result in a stroke. [...]
April 28, 2011
Do women of childbearing age and pregnant women have a special need for folate? Folic acid is very important for all women who may become pregnant. Adequate folate intake during the periconceptual period, the time just before and just after a woman becomes pregnant, protects against neural tube defects [21]. Neural tube defects result in malformations [...]
April 28, 2011
A deficiency of folate can occur when an increased need for folate is not matched by an increased intake, when dietary folate intake does not meet recommended needs, and when folate loss increases. Medications that interfere with the metabolism of folate may also increase the need for this vitamin and risk of deficiency [1,15-19]. Medical conditions that [...]
April 28, 2011
Recommendations for folate are given in the Dietary Reference Intakes (DRIs) developed by the Institute of Medicine of the National Academy of Sciences [10]. Dietary Reference Intakes is the general term for a set of reference values used for planning and assessing nutrient intake for healthy people. Three important types of reference values included in the DRIs are Recommended [...]
April 28, 2011
Folate: What is it? Folate is a water-soluble B vitamin that occurs naturally in food. Folic acid is the synthetic form of folate that is found in supplements and added to fortified foods [1]. Folate gets its name from the Latin word “folium” for leaf. A key observation of researcher Lucy Wills nearly 70 years ago led to the identification [...]
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April 28, 2011
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